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AlloDerm® Regenerative Tissue Matrix has been successfully used to repair mastoid defects for more than 7 years1
“Our results would suggest that AlloDerm provides adequate reconstruction compared with the use of fascia for the repair of mastoid bowls, especially since no resorptive rejection or extrusion was noted.”1
For additional information, please refer to full article.1
An innovative technique for mastoidectomy repair using AlloDerm® Regenerative Tissue Matrix
AlloDerm® Tissue Matrix may provide a suitable grafting material for mastoidectomy repair when fascia is either not readily available, or the size of the defect precludes the use of the fascia. The product is readily available and clinical experience has shown it to deliver comparable hearing results to fascia-repaired cases.1 In published data, when AlloDerm® Tissue Matrix is used in mastoidectomy cases to line the mastoid cavity, the epithelialization process is comparable to autologous tissue. The study also shows that the healing process is significantly faster than the alternative of not using a graft.1 This improved healing time may result in fewer complications for the patient.

AlloDerm® Tissue Matrix has been used in a variety of soft-tissue repair procedures in more than one million grafts and implants to date. It supports tissue regeneration by allowing rapid revascularization, white cell migration and cell repopulation2, which can minimize the risk of infection of the implant. Ultimately it is transformed into host tissue for a strong, natural repair. AlloDerm® Tissue Matrix is derived from natural tissue which is processed using a proprietary technique to remove the cells that can lead to tissue rejection and graft failure. The resulting acellular tissue matrix is strong, optimizing outcomes for soft-tissue repair procedures, including ENT applications, challenging hernia repair and breast reconstruction post-mastectomy.
References:- Weber PC, MD, et al. Use of AlloDerm in the Neurotologic Setting. Am Journ of Otolaryn. 2002 May;23(3):148-152.
- Connor J, et al. Retention of structural and biochemical integrity in a biological mesh supports tissue remodeling in a primate abdominal wall model. Regenerative Medicine. 2009 (in press).
Before use, physicians should review all risk information and essential prescribing information which can be found in the AlloDerm® Regenerative Tissue Matrix Instructions for Use. |
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